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TMPyP4 tosylate

TMPyP4 tosylate (TMP 1363) 是四链体 (G-quadruplex) 的特异性配体，抑制四链体和 IGF-1 之间的相互作用。它也是端粒酶抑制剂，在骨肉瘤细胞系中显示抗肿瘤作用。

CAS号

36951-72-1

分子式

C72H66N8O12S4

主要靶点

Telomerase|DNA/RNA Synthesis

仅限科研使用

Cat No : CM04315

Print datasheet

Synonyms

TMP 1363

验证数据展示

  • CAS No.: 36951-72-1

    TMPyP4 tosylate
    CAS#: 36951-72-1

产品信息

TMPyP4 tosylate is a quadruplex-specific ligand and is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines.

CAS号 36951-72-1
分子式 C72H66N8O12S4
主要靶点 Telomerase|DNA/RNA Synthesis
主要通路 DNA损伤和修复|细胞周期
分子量 1363.6
纯度 99.11%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 TMP 1363

溶解度

DMSO:10 mg/mL (7.33 mM),Sonification is recommended.,H2O:6.2 mg/mL (4.55 mM),Sonification is recommended.

参考文献

1.Fujimori J, et al. Antitumor effects of telomerase inhibitor TMPyP4 in osteosarcoma cell lines. J Orthop Res. 2011 Nov;29(11):1707-11.
2.Chen H, et al. Insuline-like growth factor type I selectively binds to G-quadruplex structures. Biochim Biophys Acta Gen Subj. 2019 Jan;1863(1):31-38.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2