TLR4 Polyclonal antibody

TLR4 Polyclonal Antibody for ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat and More (1)

Applications

ELISA and More (2)

Conjugate

Unconjugated

Cat No : 19501-1-AP

Print datasheet

Synonyms

ARMD10, CD284, hToll, TLR4, TOLL, toll like receptor 4



产品信息

19501-1-AP targets TLR4 in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications ELISA
Cited ApplicationsWB, IHC
Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, rat, pig
Immunogen Peptide 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name toll-like receptor 4
Synonyms ARMD10, CD284, hToll, TLR4, TOLL, toll like receptor 4
Calculated Molecular Weight 96 kDa
GenBank Accession NumberNM_138554
Gene Symbol TLR4
Gene ID (NCBI) 7099
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDO00206
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

TLR4, also named CD284, belongs to the Toll-like receptor family. TLR4 cooperates with LY96 and CD14 to mediates the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.

发表文章

SpeciesApplicationTitle
pigWB

Nutrients

The Effect of an Essential Oil Blend on Growth Performance, Intestinal Health, and Microbiota in Early-Weaned Piglets

Authors - Yirui Shao
ratIHC

Nutr Metab (Lond)

Combined treatment with glucosamine and chondroitin sulfate improves rheumatoid arthritis in rats by regulating the gut microbiota

Authors - Xuesong Wang
mouseWB

Fitoterapia

Chemical constituents from Eupatorium fortunei and their anti-inflammatory evaluation by in silico and experimental approaches

Authors - Lei Miao
mouseWB

J Chem Neuroanat

Suanzaoren decoction improves depressive-like behaviors by regulating the microbiota-gut-brain axis via inhibiting TLR4/NFκB/NLRP3 inflammation signal pathway

Authors - Yiyang Du
mouseWB

J Ethnopharmacol

The dichloromethane extract of Callicarpa longissima rich in diterpenoid phenols exerts anti-inflammatory effect via inhibiting the TLR4/NF-κB signaling pathway

Authors - Lian-Chun Li
mouseWB

J Microbiol Biotechnol

Thymol Ameliorates Aspergillus fumigatus Keratitis by Downregulating the TLR4/ MyD88/ NF-kB/ IL-1β Signal Expression and Reducing Necroptosis and Pyroptosis

Authors - Limei Wang