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THOC3 Polyclonal antibody

THOC3 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

Cat No : 11716-1-AP

Print datasheet

Synonyms

hTREX45, TEX1, TEX1 homolog, THO complex 3, THO complex subunit 3, Tho3, THOC3

验证数据展示

  • WB analysis using 11716-1-AP

    WB analysis using 11716-1-AP

    HEK-293 cells were subjected to SDS PAGE followed by western blot with 11716-1-AP (THOC3 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inHEK-293 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

11716-1-AP targets THOC3 in WB, ELISA applications and shows reactivity with human samples.

Tested Applications WB, ELISA
Tested Reactivity human
Immunogen THOC3 fusion protein Ag2289 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name THO complex 3
Synonyms hTREX45, TEX1, TEX1 homolog, THO complex 3, THO complex subunit 3, Tho3, THOC3
Calculated Molecular Weight 327 aa, 36 kDa
Observed Molecular Weight39 kDa
GenBank Accession NumberBC006849
Gene Symbol THOC3
Gene ID (NCBI) 84321
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ96J01
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

THOC3 is a component of the nuclear THO transcription elongation complex, which is a part of the larger transcription export (TREX) complex that couples messenger RNA processing and export. Additionally, THOC3 plays a key role in many cellular mechanisms, such as in the pathogenesis of cancer and neurodegenerative diseases (PMID: 36674977). THOC3 has 2 isoforms with the molecular weights of 36 and 39 kDa.

实验方案

Product Specific Protocols
WB protocol for THOC3 antibody 11716-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols