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TFMB-(R)-2-HG

TFMB-(R)-2-HG 是一种具有细胞膜渗透性的 (R)-2-HG，急性髓细胞性白血病的致癌因子。它能够响应雌激素戒断损害 SCF ER-Hoxb8 细胞分化。

CAS号

1445700-01-5

分子式

C13H11F3O4

主要靶点

Others

仅限科研使用

Cat No : CM05435

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Synonyms

验证数据展示

  • CAS No.: 1445700-01-5

    TFMB-(R)-2-HG
    CAS#: 1445700-01-5

产品信息

TFMB-(R)-2-HG is a carcinogenic factor in Acute myeloid leukemia (AML). TFMB-(R)-2-HG impairs SCF ER-Hoxb8 cell differentiation in response to estrogen withdrawal.

CAS号 1445700-01-5
分子式 C13H11F3O4
主要靶点 Others
主要通路 其他
分子量 288.22
纯度 99.10%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名

溶解度

DMSO:240 mg/mL (832.7 mM)

参考文献

1.Losman JA, et al. (R)-2-hydroxyglutarate is sufficient to promote leukemogenesis and its effects are reversible. Science. 2013 Mar 29;339(6127):1621-5.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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C1   V1   C2   V2