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Solcitinib

CAS号

1206163-45-2

分子式

C22H23N5O2

主要靶点

JAK

仅限科研使用

Cat No : CM04906

Print datasheet

Synonyms

Solcitinib|索西替尼|Inhibitor|inhibit|Janus kinase|JAK1|JAK|GSK2586184|GSK-2586184|GSK 2586184|GLPG0778|GLPG-0778|GLPG 0778

验证数据展示

  • CAS No.: 1206163-45-2

    Solcitinib
    CAS#: 1206163-45-2

产品信息

CAS号 1206163-45-2
分子式 C22H23N5O2
主要靶点 JAK
主要通路 表观遗传|蛋白酪氨酸激酶|干细胞|血管生成|JAK/STAT 信号通路
分子量 389.45
纯度 99.82%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 Solcitinib|索西替尼|Inhibitor|inhibit|Janus kinase|JAK1|JAK|GSK2586184|GSK-2586184|GSK 2586184|GLPG0778|GLPG-0778|GLPG 0778

靶点活性

JAK1:8-9 nM

溶解度

DMSO:10 mg/mL (25.68 mM)

参考文献

1.Kahl L, et al. Lupus. 2016 Apr 6. pii: 0961203316640910.;
2.Nakayamada S, et al. Expert Opin Pharmacother. 2016 Oct 3.;
3.Chen C, Lu M, Lin S, et al. The nuclear gene rpl18 regulates erythroid maturation via JAK2-STAT3 signaling in zebrafish model of Diamond–Blackfan anemia[J]. Cell Death & Disease. 2020, 11(2): 1-11.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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C1   V1   C2   V2