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Silymarin

CAS号

65666-07-1

分子式

C25H22O10

主要靶点

SARS-CoV

仅限科研使用

Cat No : CM00497

Print datasheet

Synonyms

thistle|Silybin B|Silymarin|SARS coronavirus|SARSCoV|SARS-CoV|水飞蓟素|insulin|Inhibitor|Milk|resistance|proliferation|hepatocellular|HCC|inhibit|carcinoma|chemopreventive|angiogenesis

验证数据展示

  • CAS No.: 65666-07-1

    Silymarin
    CAS#: 65666-07-1

产品信息

CAS号 65666-07-1
分子式 C25H22O10
主要靶点 SARS-CoV
主要通路 微生物学
分子量 482.44
纯度 ， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 thistle|Silybin B|Silymarin|SARS coronavirus|SARSCoV|SARS-CoV|水飞蓟素|insulin|Inhibitor|Milk|resistance|proliferation|hepatocellular|HCC|inhibit|carcinoma|chemopreventive|angiogenesis

体内活性

Silymarin 的静脉注射LD50分别对于小鼠、大鼠、兔子为391.4 mg/kg、70.1 mg/kg、142.3 mg/kg。

体外活性

Silymarin的作用机制涉及不同的生化反应，如通过刺激聚合酶I和核糖体RNA基因的转录来增加核糖体RNA合成的速率、阻止α-糖苷环毒素的摄取，以及保护细胞膜免受自由基诱导的损伤。Silymarin还在不同阶段对UVB诱导的癌变展现出显著的保护效果，这可能通过其强大的抗氧化性质实现。

溶解度

Ethanol:1 mg/mL (2.07 mM);DMSO:45 mg/mL (93.28 mM);H2O:< 1 mg/mL (insoluble or slightly soluble)

参考文献

1.Feher J, et al. Curr Pharm Biotechnol, 2012, 13(1), 210-217.
2.Wellington K, et al. BioDrugs, 2001, 15(7), 465-489.
3.Katiyar SK, et al. J Natl Cancer Inst, 1997, 89(8), 556-566.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2