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Semaglutide

Semaglutide 是人胰高血糖素样肽-1受体激动剂，是一种人胰高血糖素样肽-1 的长效类似物。它有用于 2 型糖尿病研究的潜力。

CAS号

910463-68-2

分子式

C187H291N45O59

主要靶点

Glucagon Receptor

仅限科研使用

Cat No : CM04241

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Synonyms

司美格鲁肽|索玛鲁肽|索马鲁肽

验证数据展示

  • CAS No.: 910463-68-2

    Semaglutide
    CAS#: 910463-68-2

产品信息

Semaglutide is a glucagon-like peptide 1 receptor (GLP-1R) agonist(EC50 of 6.2 pM in a reporter assay using BHK cells expressing the human receptor).

CAS号 910463-68-2
分子式 C187H291N45O59
主要靶点 Glucagon Receptor
主要通路 G蛋白偶联受体
分子量 4114
纯度 96.92%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 司美格鲁肽|索玛鲁肽|索马鲁肽

靶点活性

GLP-1R:6.2 pM(EC50)

溶解度

DMSO:4.11 mg/mL (1 mM)

参考文献

1.Dhillon S, et al. Semaglutide: First Global Approval. Drugs. 2018 Feb;78(2):275-284.
2.Goldenberg R M , Oren S . Semaglutide: Review and Place in Therapy for Adults with Type 2 Diabetes[J]. Canadian Journal of Diabetes, 2018:S1499267118301096-.
3.Liping Z , Lingyu Z , Lin L , et al. Neuroprotective effects of the novel GLP-1 long acting analogue semaglutide in the MPTP Parkinson's disease mouse model[J]. Neuropeptides, 2018:S0143417918300684-.

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

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