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Host
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Species Reactivity
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0
Conjugate
0
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Compatible Species
0
Conjugate
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验证数据展示

  • WB analysis using 20735-1-AP (same clone as 20735-1-PBS)

    WB analysis using 20735-1-AP (same clone as 20735-1-PBS)

    Y79 cells were subjected to SDS PAGE followed by western blot with 20735-1-AP (SYNM antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. SYNM gene methylation in T-47D cells causes gene silencing. This data was developed using the same antibody clone with 20735-1-PBS in a different storage buffer formulation.

  • IHC staining of human skeletal muscle using 20735-1-AP (same clone as 20735-1-PBS)

    IHC staining of human skeletal muscle using 20735-1-AP (same clone as 20735-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human skeletal muscle using 20735-1-AP (SYNM antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 20735-1-PBS in a different storage buffer formulation.

  • IHC staining of human skeletal muscle using 20735-1-AP (same clone as 20735-1-PBS)

    IHC staining of human skeletal muscle using 20735-1-AP (same clone as 20735-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human skeletal muscle using 20735-1-AP (SYNM antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 20735-1-PBS in a different storage buffer formulation.

  • IF Staining of HeLa using 20735-1-AP (same clone as 20735-1-PBS)

    IF Staining of HeLa using 20735-1-AP (same clone as 20735-1-PBS)

    Immunofluorescent analysis of HeLa cells using 20735-1-AP (SYNM antibody) at dilution of 1:25 and Rhodamine-Goat anti-Rabbit IgG. This data was developed using the same antibody clone with 20735-1-PBS in a different storage buffer formulation.

SYNM Polyclonal antibody, PBS Only

SYNM Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 20735-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, IF/ICC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

20735-1-PBS targets SYNM in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human
免疫原 Peptide 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 synemin, intermediate filament protein
别名
计算分子量 173 kDa
观测分子量 170-180 kDa
GenBank蛋白编号NM_015286
基因名称 SYNM
Gene ID (NCBI) 23336
RRIDAB_11042328
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDO15061
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SYNM, also named as DMN, KIAA0353 and SYN, belongs to the intermediate filament family. SYNM is a Type-VI intermediate filament (IF) which plays an important cytoskeletal role within the muscle cell cytoskeleton. It forms heteropolymeric IFs with desmin and/or vimentin, and via its interaction with cytoskeletal proteins alpha-dystrobrevin, dystrophin, talin-1, utrophin and vinculin, is able to link these heteropolymeric IFs to adherens-type junctions, such as to the costameres, neuromuscular junctions, and myotendinous junctions within striated muscle cells. The antibody can't recognize isoform 2 or 3 of SYNM.