SU5204

CAS号

186611-11-0

分子式

C17H15NO2

主要靶点

EGFR|HER|VEGFR

仅限科研使用

Cat No : CM06868

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Synonyms

3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one|EGFR|Epidermal growth factor receptor|ErbB-1|HER1|HER2|inhibit|SU 5204|SU5204|SU-5204|Vascular endothelial growth factor receptor|VEGFR2|VEGFR|Inhibitor



产品信息

CAS号 186611-11-0
分子式 C17H15NO2
主要靶点 EGFR|HER|VEGFR
主要通路 JAK/STAT 信号通路|蛋白酪氨酸激酶|血管生成|血管生成|蛋白酪氨酸激酶|蛋白酪氨酸激酶|JAK/STAT 信号通路|血管生成
分子量 265.31
纯度 99.5%, 此纯度可做参考,具体纯度与批次有关系,可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one|EGFR|Epidermal growth factor receptor|ErbB-1|HER1|HER2|inhibit|SU 5204|SU5204|SU-5204|Vascular endothelial growth factor receptor|VEGFR2|VEGFR|Inhibitor

靶点活性

HER2:51.5 μM|VEGFR2:4 μM

溶解度

DMSO:27.5 mg/mL (103.65 mM)

参考文献

1.Peng Cho Tang, et al. 3-heteroaryl-2-indolinone compounds for the treatment of disease. US5792783A.

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The dilution calculator equation

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