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Host
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Species Reactivity
0
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0
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验证数据展示

  • WB analysis using 14609-1-AP (same clone as 14609-1-PBS)

    WB analysis using 14609-1-AP (same clone as 14609-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 14609-1-AP (SMPD1,ASM antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14609-1-PBS in a different storage buffer formulation.

  • IHC staining of human brain using 14609-1-AP (same clone as 14609-1-PBS)

    IHC staining of human brain using 14609-1-AP (same clone as 14609-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 14609-1-AP (SMPD1,ASM Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14609-1-PBS in a different storage buffer formulation.

  • IHC staining of human brain using 14609-1-AP (same clone as 14609-1-PBS)

    IHC staining of human brain using 14609-1-AP (same clone as 14609-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 14609-1-AP (SMPD1,ASM Antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14609-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

SMPD1,ASM Polyclonal antibody, PBS Only

SMPD1,ASM Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 14609-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

14609-1-PBS targets SMPD1,ASM in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原 SMPD1,ASM fusion protein Ag6180 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 sphingomyelin phosphodiesterase 1, acid lysosomal
别名
计算分子量 70 kDa
观测分子量60 kDa, 70-75 kDa
GenBank蛋白编号BC041164
基因名称 SMPD1
Gene ID (NCBI) 6609
RRIDAB_2878068
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP17405
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SMPD1(Sphingomyelin phosphodiesterase) is also named as ASM and belongs to the acid sphingomyelinase family. It is an important enzyme in sphingolipid metabolism and plays key roles in apoptosis, immunity, development, and cancer. The deficient activity of this enzyme results in Types A and B Niemann-Pick disease (NPD). This protein has 4 isoforms produced by alternative splicing. SMPD1 can produce a 60 kDa peptide with its signal peptide missing.