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验证数据展示

  • WB analysis using 20299-1-AP (same clone as 20299-1-PBS)

    WB analysis using 20299-1-AP (same clone as 20299-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 20299-1-AP (SLC6A8 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20299-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 20299-1-AP (same clone as 20299-1-PBS)

    IHC staining of mouse brain using 20299-1-AP (same clone as 20299-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 20299-1-AP (SLC6A8 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20299-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse brain using 20299-1-AP (same clone as 20299-1-PBS)

    IF Staining of mouse brain using 20299-1-AP (same clone as 20299-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse brain tissue using 20299-1-AP (SLC6A8 antibody) at dilution of 1:50 and CoraLite488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 20299-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 20299-1-AP (same clone as 20299-1-PBS)

    IHC staining of mouse brain using 20299-1-AP (same clone as 20299-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 20299-1-AP (SLC6A8 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20299-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

SLC6A8 Polyclonal antibody, PBS Only

SLC6A8 Polyclonal Antibody for WB, IHC, IF-P, Indirect ELISA
Cat No. 20299-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, IF-P, Indirect ELISA

别名

Sodium- and chloride-dependent creatine transporter 1, CT1, CRTR, CRT, Creatine transporter 1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

20299-1-PBS targets SLC6A8 in WB, IHC, IF-P, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, IF-P, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 SLC6A8 fusion protein Ag14110 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 solute carrier family 6 (neurotransmitter transporter, creatine), member 8
别名 Sodium- and chloride-dependent creatine transporter 1, CT1, CRTR, CRT, Creatine transporter 1
计算分子量 635 aa, 71 kDa
观测分子量 65-70 kDa
GenBank蛋白编号BC012355
基因名称 SLC6A8
Gene ID (NCBI) 6535
RRIDAB_2878665
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP48029
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SLC6A8, also known as the sodium- and chloride-dependent creatine transporter 1 (CT1), plays a critical role in transporting creatine, a crucial molecule for energy metabolism, into cells. SLC6A8 belongs to the solute carrier family 6 (SLC6), responsible for transporting diverse molecules across cell membranes. SLC6A8 expression is highest in muscle, kidney, and other tissues with high energy demands. Mutations in SLC6A8 cause creatine transporter deficiency, an X-linked mental retardation disorder (PMID: 17465020).