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验证数据展示

  • IHC staining of human colon cancer using 21287-1-AP (same clone as 21287-1-PBS)

    IHC staining of human colon cancer using 21287-1-AP (same clone as 21287-1-PBS)

    Immunohistochemical analysis of paraffin-embedded Colorectal cancer slide using 21287-1-AP (SLC39A2 antibody) at dilution of 1:100 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21287-1-PBS in a different storage buffer formulation.

  • WB analysis using 21287-1-AP (same clone as 21287-1-PBS)

    WB analysis using 21287-1-AP (same clone as 21287-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 21287-1-AP (SLC39A2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21287-1-PBS in a different storage buffer formulation.

  • IHC staining of human colon cancer using 21287-1-AP (same clone as 21287-1-PBS)

    IHC staining of human colon cancer using 21287-1-AP (same clone as 21287-1-PBS)

    Immunohistochemical analysis of paraffin-embedded Colorectal cancer slide using 21287-1-AP (SLC39A2 antibody) at dilution of 1:100 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21287-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 21287-1-AP (same clone as 21287-1-PBS)

    IHC staining of mouse brain using 21287-1-AP (same clone as 21287-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 21287-1-AP (SLC39A2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21287-1-PBS in a different storage buffer formulation.

SLC39A2 Polyclonal antibody, PBS Only

SLC39A2 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 21287-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, Indirect ELISA

别名

ZIP-2, ZIP2, hZIP2, Eti-1, Eti 1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

21287-1-PBS targets SLC39A2 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原 SLC39A2 fusion protein Ag15807 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 solute carrier family 39 (zinc transporter), member 2
别名 ZIP-2, ZIP2, hZIP2, Eti-1, Eti 1
计算分子量 309 aa, 33 kDa
观测分子量33 kDa, 66-70 kDa
GenBank蛋白编号BC096723
基因名称 SLC39A2
Gene ID (NCBI) 29986
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9NP94
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SLC39A2 (hZIP2) is a human zinc importer in the ZIP family, which is essential in the maintenance of intracellular zinc homeostasis and is upregulated by zinc depletion. SLC39A2 is highly expressed in prostate epithelial cells and is involved in prostate cancer development. Most SLC39 proteins consist of eight transmembrane domains (TMDs), with extracellular or intravesicular amino and carboxy termini (PMID: 34790705). Zip2 gene knockout exacerbated myocardial I/R injury, whereas Zip2 gene transfer reduced myocardial infarction (PMID: 31095941). The predicted molecular weight of SLC39A2 is 33 kDa, and a band of dimers at 66 kDa can also be detected by this antibody (PMID: 24619115).