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SLC17A5 Polyclonal antibody

SLC17A5 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Conjugate

Unconjugated

Cat No : 13320-1-AP

Print datasheet

Synonyms

AST, ISSD, Membrane glycoprotein HP59, NSD, SD, SIALIN, SIASD, SLC17A5, SLD

验证数据展示

  • WB analysis of human kidney using 13320-1-AP

    WB analysis of human kidney using 13320-1-AP

    human kidney tissue were subjected to SDS PAGE followed by western blot with 13320-1-AP (SLC17A5 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inhuman kidney tissue, HEK-293 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

13320-1-AP targets SLC17A5 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, ELISA
Tested Reactivity human, mouse, rat
Immunogen SLC17A5 fusion protein Ag3855 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name solute carrier family 17 (anion/sugar transporter), member 5
Synonyms AST, ISSD, Membrane glycoprotein HP59, NSD, SD, SIALIN, SIASD, SLC17A5, SLD
Calculated Molecular Weight 495 aa, 55 kDa
Observed Molecular Weight 31 kDa
GenBank Accession NumberBC020961
Gene Symbol SLC17A5
Gene ID (NCBI) 26503
RRIDAB_2187524
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9NRA2
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

SLC17A5 encodes a transmembrane protein, sialin, which transports free sialic acid across the lysosomal membrane. Mutations in sialin result in neurodegenerative sialic acid storage disorders, Salla disease (SD) and infantile sialic acid storage disease (ISSD). In the central nervous system, sialin is more abundant in neurons than in glia. It has been reported to be localized into lysosome in neuron but in plasma membrane in nonneuronal cells (PMID: 15006695).

实验方案

Product Specific Protocols
WB protocol for SLC17A5 antibody 13320-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols