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验证数据展示

  • WB analysis of mouse thymus using 11868-1-AP (same clone as 11868-1-PBS)

    WB analysis of mouse thymus using 11868-1-AP (same clone as 11868-1-PBS)

    mouse thymus tissue were subjected to SDS PAGE followed by western blot with 11868-1-AP (SH2D1A antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11868-1-PBS in a different storage buffer formulation.

SH2D1A Polyclonal antibody, PBS Only

SH2D1A Polyclonal Antibody for WB, Indirect ELISA
Cat No. 11868-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

11868-1-PBS targets SH2D1A in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag2450

Product name: Recombinant human SH2D1A protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-128 aa of BC020732

Sequence: MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKKSSARSTQGTTGIREDPDVCLKAP

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 SH2 domain protein 1A
别名
计算分子量 128 aa, 14 kDa
观测分子量 16 kDa
GenBank蛋白编号BC020732
基因名称 SH2D1A
Gene ID (NCBI) 4068
RRIDAB_2239283
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDO60880
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SH2D1A, also named as DSHP and SAP, is an inhibitor of the SLAM self-association. It acts by blocking recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to a docking site in the SLAM cytoplasmic region. SH2D1A mediates interaction between FYN and SLAMF1. Defects in SH2D1A are a cause of lymphoproliferative syndrome X-linked type 1 (XLP1).