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SC-26196

CAS号

218136-59-5

分子式

C27H29N5

主要靶点

Others

仅限科研使用

Cat No : CM03626

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Synonyms

Antiinflammatory|ALPHA,ALPHA-二苯基-4-[(3-吡啶亚甲基)氨基]-1-吡嗪戊腈|inflammatory|inhibit|FADS2|disease|D6D|desaturase|Delta6|Delta6 desaturase in a rat liver microsomal assay|SC26196|SC-26196|SC 26196|Inhibitor

验证数据展示

  • CAS No.: 218136-59-5

    SC-26196
    CAS#: 218136-59-5

产品信息

CAS号 218136-59-5
分子式 C27H29N5
主要靶点 Others
主要通路 其他
分子量 423.55
纯度 99.72%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 Antiinflammatory|ALPHA,ALPHA-二苯基-4-[(3-吡啶亚甲基)氨基]-1-吡嗪戊腈|inflammatory|inhibit|FADS2|disease|D6D|desaturase|Delta6|Delta6 desaturase in a rat liver microsomal assay|SC26196|SC-26196|SC 26196|Inhibitor

靶点活性

Delta6 desaturase (rat liver microsomal assay):0.2 μM

体外活性

The FADS2 inhibitor SC26196 reduced PBMC, but not Jurkat cell, proliferation suggesting PUFA synthesis is involved in regulating mitosis in PBMCs[1].

溶解度

DMSO:4 mg/mL (9.44 mM)

参考文献

1.Sibbons CM, et al. Polyunsaturated Fatty Acid Biosynthesis Involving Δ8 Desaturation and Differential DNA Methylation of
2.Obukowicz MG, et al. Novel, selective delta6 or delta5 fatty acid desaturase inhibitors as antiinflammatory agents in mice. J Pharmacol Exp Ther. 1998 Oct;287(1):157-66.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

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