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SBC-115076

SBC-115076 是前蛋白转化酶枯草杆菌蛋白酶/ kexin 9型(PCSK9)抑制剂。其中PCSK9 是一种前蛋白转化酶，在 LDL 受体代谢中的重要物质。

CAS号

489415-96-5

分子式

C31H33N3O5

主要靶点

Others|Serine/threonin kinase

仅限科研使用

Cat No : CM05603

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Synonyms

SBC115076

验证数据展示

  • CAS No.: 489415-96-5

    SBC-115076
    CAS#: 489415-96-5

产品信息

SBC-115076 is a potent extracellular proprotein convertase subtilisin kexin type 9 (PCSK9) antagonist.

CAS号 489415-96-5
分子式 C31H33N3O5
主要靶点 Others|Serine/threonin kinase
主要通路 其他|细胞周期|代谢
分子量 527.61
纯度 99.39%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 SBC115076

体内活性

In mice that are fed high fat diet, SBC-115076 (8 mg/kg) lowers cholesterol levels by 32%. [1]

体外活性

In HepG2 cells, SBC-115076 increases the uptake of Fluorescent Dil-LDL. [1]

溶解度

H2O:<1 mg/mL,Ethanol:<1 mg/mL,DMSO:93 mg/mL (176.3 mM)

参考文献

1.Abdel-Meguid SS, et al. WO2014150326 A1.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
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C1   V1   C2   V2