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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 29318-1-AP (same clone as 29318-1-PBS)

    WB analysis using 29318-1-AP (same clone as 29318-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 29318-1-AP (S1PR1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29318-1-PBS in a different storage buffer formulation.

S1PR1/EDG1 Polyclonal antibody, PBS Only

S1PR1/EDG1 Polyclonal Antibody for WB, Indirect ELISA
Cat No. 29318-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, Indirect ELISA

别名

S1PR1, EDG1, EDG 1, ECGF1, D1S3362

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

29318-1-PBS targets S1PR1/EDG1 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原 S1PR1/EDG1 fusion protein Ag28083 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 sphingosine-1-phosphate receptor 1
别名 S1PR1, EDG1, EDG 1, ECGF1, D1S3362
计算分子量 43 kDa
观测分子量45-50 kDa
GenBank蛋白编号BC018650
基因名称 S1PR1
Gene ID (NCBI) 1901
RRIDAB_2918281
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP21453
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

S1PR1 (sphingosine-1-phosphate receptor 1), also known as S1P1 or EDG1, is one of five G-protein-coupled receptors for sphingosine-1-phosphate (S1P) (PMID: 18787560). S1P1 and its receptors have important regulatory functions in normal physiology and disease processes, particularly involving the immune, central nervous, and cardiovascular systems (PMID: 21339489). S1PR1 is widely expressed in various cell types, including endothelial cells and lymphocytes (PMID: 14737169). S1P-S1PR1 plays a major role in lymphocyte egress and chemotaxis, cell proliferation and survival, and tumor angiogenesis and metastasis (PMID: 21102457).