Roquinimex

Roquinimex (FCF89) 是一种喹啉衍生物免疫刺激剂,可增加 NK 细胞活性和巨噬细胞的细胞毒性,抑制血管生成并减少 TNF α 的分泌。

CAS号

84088-42-6

分子式

C18H16N2O3

主要靶点

TNF

仅限科研使用

Cat No : CM06687

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Synonyms

FCF89|ABR212616|Linomide|LS2616|罗喹美克



产品信息

Roquinimex (Linomide) is a quinoline derivative immunostimulant which increases NK cell activity and macrophage cytotoxicity; inhibits angiogenesis and reduces the secretion of TNF alpha.

CAS号 84088-42-6
分子式 C18H16N2O3
主要靶点 TNF
主要通路 凋亡
分子量 308.34
纯度 99.65%, 此纯度可做参考,具体纯度与批次有关系,可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 FCF89|ABR212616|Linomide|LS2616|罗喹美克

溶解度

DMSO:83.3 mg/mL (270.17 mM)

参考文献

1.Liu Q,etal. Roquinimex inhibits dextran sodium sulfate-induced murine colitis.Inflamm Res. 2003 Feb;52(2):64-8.
2.Tian WZ,etal.Linomide (roquinimex) affects the balance between pro- and anti-inflammatory cytokines in vitro in multiple sclerosis.Acta Neurol Scand. 1998 Aug;98(2):94-101.

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The dilution calculator equation

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