Recombinant ADPRHL1 / ARH2 protein

A representative Technical Data Sheet (TDS) is provided here. Please refer to the lot-specific TDS you will receive with your order for the lot-specific buffer contents and protein concentration.

Protein ADP-ribosylation is a highly dynamic post-translational modification. The rapid turnover is achieved, among others, by ADP (ribosyl)hydrolases (ARHs), an ancient family of enzymes that reverses this modification. Recently ARHs came into focus due to their role as regulators of cellular stresses and tumor suppressors.ADPRHL1 / ARH2 (Inactive ADP-ribosyltransferase ARH2) as one of ARHs,is required for myofibril assembly and outgrowth of the cardiac chambers in the developing heart,but does not appears to be catalytically inactive, showing no activity against O-acetylADP-ribose.

This product was manufactured as described in Protein Details. Where possible, Active Motif has developed functional or activity assays for recombinant proteins. Additional characterization such as enzyme kinetic activity assays, inhibitor screening or other biological activity assays may not have been performed for every product. All available data for a given product is shown on the lot-specific Technical Data Sheet.

Recombinant ADPRHL1 / ARH2 protein that includes full length of the human ADPRHL1 / ARH2 protein (accession number NP_612439.2) was expressed in E.coli cells with an C-terminal His tag, The molecular weight of the protein is 41.17 kDa.

Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

This product is guaranteed for 6 months from date of receipt.

This product is for research use only and is not for use in diagnostic procedures.