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Recombinant Rat Lipocalin-2/NGAL protein (His Tag)

种属

Rat

纯度

>90 %, SDS-PAGE

标签

His Tag

生物活性

未测试

Cat no : Eg1022

Print datasheet

Synonyms

Lcn2, Lipocalin2/NGAL, Alpha-2-microglobulin-related protein, Alpha-2U globulin-related protein, lipocalin 2

验证数据展示

  • Purity of Recombinant Rat Lipocalin-2 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Rat Lipocalin-2 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 Not tested
来源 HEK293-derived Rat Lipocalin-2 protein Gln21-Asn198 (Accession# P30152) with a His tag at the C-terminus.
基因ID 170496
蛋白编号 P30152
预测分子量 21.6 kDa
SDS-PAGE 22-26 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

Neutrophil gelatinase-associated lipocalin (NGAL, also known as lipocalin-2, siderocalin, or LCN2) is a small molecule of almost 25 kDa that belongs to the well-defined superfamily of proteins called lipocalins. NGAL was initially found in activated neutrophils, under its role as an innate antibacterial factor. However, it subsequently was shown that many other types of cells, including in the kidney tubule, may produce NGAL in response to various injuries. NGAL may become one of the most promising next-generation biomarkers in clinical nephrology and beyond.

参考文献:

1. Lim D, et al. (2021) CNS Neurosci Ther.27:883-94.
2. Kjeldsen L, et al. (1993) J Biol Chem.268:10425-32.
3. Devireddy LR, et al. (2005) Cell.123:1293-305.
4. Xing C, et al. (2014) Stroke.45:2085-92.
5. Asaf S, et al. (2023) Immunol Res.71:287-313.