验证数据展示
产品信息
27099-1-PBS targets RUNX3 in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag24339 Product name: Recombinant human RUNX3 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 207-251 aa of BC013362 Sequence: PFPDRFGDLERLRMRVTPSTPSPRGSLSTTSHFSSQPQTPIQGTS 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | runt-related transcription factor 3 |
| 别名 | AML2, CBF alpha 3, CBFA3, CBF-alpha-3, Core-binding factor subunit alpha-3 |
| 计算分子量 | 44 kDa |
| 观测分子量 | 45-55 kDa |
| GenBank蛋白编号 | BC013362 |
| 基因名称 | RUNX3 |
| Gene ID (NCBI) | 864 |
| RRID | AB_2880754 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q13761 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
RUNX3, also known as AML2, CBFA3 and PEBP2A3, is a member of the RUNX family of transcription factors, which are crucial regulators of embryonic development and play key roles in various biological processes such as cell proliferation, apoptosis, differentiation and lineage commitment (PMID: 38430423). This protein functions as a tumour suppressor and is frequently deleted or transcriptionally silenced in various cancers, including gastric and colon cancer.
