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验证数据展示

  • WB analysis of mouse skeletal muscle using 11168-1-AP (same clone as 11168-1-PBS)

    WB analysis of mouse skeletal muscle using 11168-1-AP (same clone as 11168-1-PBS)

    mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 11168-1-AP (RTN2 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11168-1-PBS in a different storage buffer formulation.

  • IHC staining of human skeletal muscle using 11168-1-AP (same clone as 11168-1-PBS)

    IHC staining of human skeletal muscle using 11168-1-AP (same clone as 11168-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human skeletal muscle slide using 11168-1-AP (RTN2 Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 11168-1-PBS in a different storage buffer formulation.

  • IHC staining of human skeletal muscle using 11168-1-AP (same clone as 11168-1-PBS)

    IHC staining of human skeletal muscle using 11168-1-AP (same clone as 11168-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human skeletal muscle slide using 11168-1-AP (RTN2 Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 11168-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

RTN2 Polyclonal antibody, PBS Only

RTN2 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 11168-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

Neuroendocrine-specific protein-like 1, Neuroendocrine-specific protein-like I, NSPL1, NSPLI, NSP-like protein 1

缓冲液配方:  PBS Only
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

11168-1-PBS targets RTN2 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag1655

Product name: Recombinant human RTN2 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 344-545 aa of BC014244

Sequence: KVADLLYWKDTRTSGVVFTGLMVSLLCLLHFSIVSVAAHLALLLLCGTISLRVYRKVLQAVHRGDGANPFQAYLDVDLTLTREQTERLSHQITSRVVSAATQLRHFFLVEDLVDSLKLALLFYILTFVGAIFNGLTLLILGVIGLFTIPLLYRQHQAQIDQYVGLVTNQLSHIKAKIRAKIPGTGALASAAAAVSGSKAKAE

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 reticulon 2
别名 Neuroendocrine-specific protein-like 1, Neuroendocrine-specific protein-like I, NSPL1, NSPLI, NSP-like protein 1
计算分子量 59 kDa, 51 kDa, 22 kDa
观测分子量 20-23 kDa
GenBank蛋白编号BC014244
基因名称 RTN2
Gene ID (NCBI) 6253
RRIDAB_10644321
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDO75298
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Reticulon (RTN) proteins are a group of membrane-bound proteins that largely reside in endoplasmic reticulum (ER) (PMID: 18177508). Reticulon proteins share a common sequence feature, the reticulon homology domain (RHD). They are involved in shaping the tubular endoplasmic reticulum network, membrane trafficking, inhibition of axonal growth, and apoptosis (PMID: 24218324). Four mammalian reticulons (RTN1-4) exist. The human RTN2 gene produces three isoforms termed RTN2-A, RTN2-B, and RTN2-C. Isoform RTN2-C has a calculated molecular weight of 22 kDa and is highly expressed in skeletal muscle.

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