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RG2833

CAS号

1215493-56-3

分子式

C20H25N3O2

主要靶点

HDAC

仅限科研使用

Cat No : CM04428

Print datasheet

Synonyms

inhibit|Histone deacetylases|HDAC|HDAC1|HDAC3|Inhibitor|RG 2833|RGFP109|RGFP-109|RGFP 109|RG2833|RG-2833

验证数据展示

  • CAS No.: 1215493-56-3

    RG2833
    CAS#: 1215493-56-3

产品信息

CAS号 1215493-56-3
分子式 C20H25N3O2
主要靶点 HDAC
主要通路 DNA 损伤和修复|表观遗传
分子量 339.43
纯度 99.13%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 inhibit|Histone deacetylases|HDAC|HDAC1|HDAC3|Inhibitor|RG 2833|RGFP109|RGFP-109|RGFP 109|RG2833|RG-2833

靶点活性

HDAC1:32 nM(Ki)|HDAC3:5 nM(Ki)

体外活性

In unstimulated peripheral blood mononuclear cells, RG2833 upregulates the level of the synaptic mRNA and protein in a dose-dependent manner.

溶解度

DMSO:45 mg/mL (132.58 mM);Ethanol:10 mg/mL (29.46 mM)

参考文献

1.Rai M, et al. PLoS One. 2010, 5(1), e8825.
2.Sandi C, et al. Neurobiol Dis. 2011, 42(3), 496-505.
3.Johnston TH, et al. Parkinsonism Relat Disord. 2013, 19(2), 260-264.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
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C1   V1   C2   V2