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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 11861-1-AP (same clone as 11861-1-PBS)

    WB analysis using 11861-1-AP (same clone as 11861-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 11861-1-AP (RAMP3 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11861-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 11861-1-AP (same clone as 11861-1-PBS)

    IHC staining of human breast cancer using 11861-1-AP (same clone as 11861-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer using 11861-1-AP (RAMP3 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 11861-1-PBS in a different storage buffer formulation.

RAMP3 Polyclonal antibody, PBS Only

RAMP3 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 11861-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

11861-1-PBS targets RAMP3 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原 RAMP3 fusion protein Ag2438 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 receptor (G protein-coupled) activity modifying protein 3
别名
计算分子量16.5 kDa
观测分子量 45-50 kDa
GenBank蛋白编号BC022304
基因名称 RAMP3
Gene ID (NCBI) 10268
RRIDAB_2176465
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDO60896
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The receptor activity-modifying proteins (RAMPs) and the calcitonin receptor-like receptor (CRLR) are both required to generate adrenomedullin (AM) and calcitonin gene-related peptide (CGRP) receptors. During the process, RAMP3 transports the glycosylated 58-kD CGRPR to the cell surface. The formation of CRLR-RAMP heterodimer is essential for the proper cell surface targeting and pharmacological characteristics of both CGRP and AM receptors.