验证数据展示
经过测试的应用
Positive WB detected in | MCF-10A cells, Mo7e cells, HaCaT cells |
推荐稀释比
应用 | 推荐稀释比 |
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Western Blot (WB) | WB : 1:2000-1:10000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
68603-1-Ig targets RAB38 in WB, ELISA applications and shows reactivity with Human samples.
经测试应用 | WB, ELISA Application Description |
经测试反应性 | Human |
免疫原 | RAB38 fusion protein Ag26440 种属同源性预测 |
宿主/亚型 | Mouse / IgG2a |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | RAB38, member RAS oncogene family |
别名 | Melanoma antigen NY MEL 1, NY MEL 1, RAB38, Ras related protein Rab 38, rrGTPbp |
计算分子量 | 211 aa, 24 kDa |
观测分子量 | 24 kDa |
GenBank蛋白编号 | BC015808 |
基因名称 | RAB38 |
Gene ID (NCBI) | 23682 |
RRID | AB_3085299 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P57729 |
储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
The RAB family of small GTPases is part of the Ras protein superfamily and is primarily responsible for regulating intracellular vesicle transport and migration. RAB38 is a recently identified member of the RAB family of proteins and its expression is tissue-specific. RAB38 is predominantly expressed in melanocytes and melanoma tissues, but not in other normal tissues, serving as a melanocyte differentiation antigen. RAB38 has also been reported to be upregulated in glioblastoma, and high levels of its expression are associated with a poor prognosis and enhanced cell migration.
实验方案
Product Specific Protocols | |
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WB protocol for RAB38 antibody 68603-1-Ig | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |