• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

R1487 HCl

R1487 HCl is highly potent and highly selective inhibitors of p38α.

CAS号

449808-64-4

分子式

C19H19ClF2N4O3

主要靶点

p38 MAPK

仅限科研使用

Cat No : CM05672

Print datasheet

Synonyms

验证数据展示

  • CAS No.: 449808-64-4

    R1487 HCl
    CAS#: 449808-64-4

  • R1487 HCl<br/>CAS#: 449808-64-4

    R1487 HCl
    CAS#: 449808-64-4

产品信息

R1487 hydrochloride is highly potent and highly selective inhibitors of p38α.

CAS号 449808-64-4
分子式 C19H19ClF2N4O3
主要靶点 p38 MAPK
主要通路 MAPK/ERK Pathway
分子量 424.829
MDL NO MFCD18711690
Pubchem ID 54580957.0
纯度 98%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件
粉末 -20°C 3年
液体 -80°C 1年
运输条件 Shipped in cold pack
别名

靶点

TargetActivity

溶解度

DMSO20 mg/mL
WaterInsoluble

参考文献

1Goldstein DM, Soth M, et al. Discovery of 6-(2,4-difluorophenoxy)-2-[3-hydroxy-1-(2-hydroxyethyl)propylamino] -8-methyl-8H-pyrido[2,3-d] pyrimidin-7-one (pamapimod) and 6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2H-pyran-4-ylamino)pyrido[2,3-d] pyrimidin-7(8H)-one (R1487) as orally bioavailable and highly selective inhibitors of p38α mitogen-activated protein kinase. J Med Chem. 2011 Apr 14;54(7):2255-65.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
=
×
×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2