R(+)-IAA-94

CAS号

54197-31-8

分子式

C17H18Cl2O4

主要靶点

Chloride channel

仅限科研使用

Cat No : CM03463

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Synonyms

Chloridechannel|chloride channel|Chloride channel|R(+)-Methylindazone|RIAA 94|RIAA94|RIAA-94|RMethylindazone



产品信息

CAS号 54197-31-8
分子式 C17H18Cl2O4
主要靶点 Chloride channel
主要通路 离子通道
分子量 357.23
纯度 99.22%, 此纯度可做参考,具体纯度与批次有关系,可咨询客服
储存条件 keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 Chloridechannel|chloride channel|Chloride channel|R(+)-Methylindazone|RIAA 94|RIAA94|RIAA-94|RMethylindazone

体外活性

IAA-94被用于调节氯通道功能,以探究其动态性和功能。IAA-94与氯通道的高亲和性被用于这些蛋白的分离和重构[1][2]。

溶解度

DMSO:90 mg/mL (251.94 mM)

参考文献

1.Landry DW, et al. Epithelial chloride channel. Development of inhibitory ligands. J Gen Physiol. 1987 Dec;90(6):779-98.
2.Landry DW, et al. Purification and reconstitution of chloride channels from kidney and trachea. Science. 1989 Jun 23;244(4911):1469-72.
3.Xiaoqin Fan, et al. A homogeneous time-resolved fluorescence-based high-throughput screening for discovery of inhibitors of Nef-sdAb19 interaction. Int J Oncol. 2015 Oct;47(4):1485-93.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
=
×
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2