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Perfluorooctanoic acid

Perfluorooctanoic acid (PFOA) 是一种持久且广泛使用的工业化学品。

CAS号

335-67-1

分子式

C8HF15O2

主要靶点

Dehydrogenase

仅限科研使用

Cat No : CM07228

Print datasheet

Synonyms

全氟辛酸|PFOA

验证数据展示

  • CAS No.: 335-67-1

    Perfluorooctanoic acid
    CAS#: 335-67-1

产品信息

Perfluorooctanoic acid (PFOA) is a persistent and widespread industry-made chemical.

CAS号 335-67-1
分子式 C8HF15O2
主要靶点 Dehydrogenase
主要通路 代谢
分子量 414.0684
纯度 100.00%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 全氟辛酸|PFOA

靶点活性

3β-HSD:53.2μM|17β-HSD3: 17.7μM

体外活性

Perfluorooctanoic acid exposure impaired the tight junction of corneal cells and caused inflammatory reactions in the retina. Exposure of the cornea to perfluorooctanoic acid contained in particulate matter might induce oxidative stress and inflammation in the retina and represent a risk factor for age-related macular degeneration[1]. PFOA had toxic effects on SMMC-7721 cells, such as inhibiting cell proliferation and inducing apoptosis[2].

溶解度

DMSO:65 mg/ml (156.98 mM)

参考文献

1.Tien P T ,  Lin H J ,  Tsai Y Y , et al. Perfluorooctanoic acid in indoor particulate matter triggers oxidative stress and inflammation in corneal and retinal cells[J]. Scientific Reports.
2.Ming, Guo, Ping, et al. Perfluorooctanoic acid exposure induces apoptosis in SMMC-7721 hepatocellular cancer cells.[J]. Environmental pollution (Barking, Essex : 1987), 2019.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
=
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2