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验证数据展示

  • IHC staining of human brain using 14357-1-AP (same clone as 14357-1-PBS)

    IHC staining of human brain using 14357-1-AP (same clone as 14357-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 14357-1-AP (PTGER3 Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 14357-1-PBS in a different storage buffer formulation.

  • IHC staining of human brain using 14357-1-AP (same clone as 14357-1-PBS)

    IHC staining of human brain using 14357-1-AP (same clone as 14357-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 14357-1-AP (PTGER3 Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 14357-1-PBS in a different storage buffer formulation.

PTGER3 Polyclonal antibody, PBS Only

PTGER3 Polyclonal Antibody for IHC, Indirect ELISA
Cat No. 14357-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

IHC, Indirect ELISA

别名

EP3, EP3 I, EP3 II, EP3 III, EP3 IV

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

14357-1-PBS targets PTGER3 in IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag5711

Product name: Recombinant human PTGER3 protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 1-374 aa of BC024229

Sequence: MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRWEHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLLALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQMRKRRLREQEEFWGN

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 prostaglandin E receptor 3 (subtype EP3)
别名 EP3, EP3 I, EP3 II, EP3 III, EP3 IV
计算分子量 43 kDa
GenBank蛋白编号BC024229
基因名称 PTGER3
Gene ID (NCBI) 5733
RRIDAB_2237964
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDP43115
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

PTGER3 (Prostaglandin E Receptor 3), also known as EP3, is a G protein-coupled receptor (GPCR). Activates pathways involved in proliferation, migration, and apoptosis, often via cross-talk with PI3K-AKT and MAPK cascades (PMID: 38566528). High PTGER3 levels drive tumorigenesis, angiogenesis, and cisplatin resistance via the Ras-MAPK/Erk-ETS1-ELK1/CFTR1 axis (PMID: 30655206).