验证数据展示
产品信息
31543-1-PBS targets PPEF2 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | human, mouse, rat |
免疫原 | PPEF2 fusion protein Ag35922 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | protein phosphatase, EF-hand calcium binding domain 2 |
别名 | |
计算分子量 | 86kDa |
观测分子量 | 69 kDa |
GenBank蛋白编号 | NM_006239 |
基因名称 | PPEF2 |
Gene ID (NCBI) | 5470 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity Purification |
UNIPROT ID | O14830 |
储存缓冲液 | PBS only, pH 7.3. |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Pprotein phosphatase with EF-hand domain 2 (PPEF2), also known as PPP7CB, is a member of the serine/threonine protein phosphatase with EF-hand motif family. PPEF2 can dephosphorylate ubiquitin and suppress PINK1-dependent mitophagy. PPEF2 functions to suppress mitochondrial quality control on a cellular level through dephosphorylation of p-S65 ubiquitin. PPEF2 exists 2 isoforms produced by alternative splicing with a molecular weight of 86 kDa (PPEF-2(L)) and 69 kDa (PPEF-2(S)).