验证数据展示
经过测试的应用
| Positive IP detected in | mouse brain tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Immunoprecipitation (IP) | IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
31835-1-AP targets PLXNC1 in IP, ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | IP, ELISA Application Description |
| 经测试反应性 | human, mouse |
| 免疫原 |
CatNo: Ag36558 Product name: Recombinant human PLXNC1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1208-1348 aa of BC156867 Sequence: IPENESADVCRNISVNVLDCDTIGQAKEKIFQAFLSKNGSPYGLQLNEIGLELQMGTRQKELLDIDSSSVILEDGITKLNTIGHYEISNGSTIKVFKKIANFTSDVEYSDDHCHLILPDSEAFQDVQGKRHRGKHKFKVKE 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | plexin C1 |
| 别名 | CD232, plexin C1, PLXN C1, VESPR |
| 计算分子量 | 1568 aa, 176 kDa |
| 观测分子量 | 150 kDa, 200 kDa |
| GenBank蛋白编号 | BC156867 |
| 基因名称 | PLXNC1 |
| Gene ID (NCBI) | 10154 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity Purification |
| UNIPROT ID | O60486 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Plexin C1 (PLXNC1) located on chromosome 12 is a member of Plexin family composed of transmembrane proteins. PLXNC1 which was first described in the optic tectum participates in neuron cell adhesion and migration as a target receptor of Semaphorin 7A. In addition to the role in nervous system, there is considerable evidence in favor of the involvement of PLXNC1 in human diseases through regulating immunological response. For example, knockdown of PLXNC1 plays the suppressive role in hepatic ischemia-reperfusion injury and lung injury through reducing inflammatory response. Nevertheless, the effects of PLXNC1 on the biological processes of OA remain to be elaborated (PMID: 37853395). PLXNC1 has multiple glycosylation sites, which may cause the observed bands to migrate differently..
实验方案
| Product Specific Protocols | |
|---|---|
| IP protocol for PLXNC1 antibody 31835-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
