验证数据展示
Planning an IHC experiment? We recommend our IHCeasy PLK3 Ready-To-Use IHC Kit. PLK3 primary antibody included.
产品信息
10977-1-PBS targets PLK3 in IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | IHC, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 | PLK3 fusion protein Ag1431 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | polo-like kinase 3 (Drosophila) |
| 别名 | PLK 3, FNK, FGF-inducible kinase, EC:2.7.11.21, Cytokine-inducible serine/threonine-protein kinase |
| 计算分子量 | 72 kDa |
| 观测分子量 | 72 kDa |
| GenBank蛋白编号 | BC013899 |
| 基因名称 | PLK3 |
| Gene ID (NCBI) | 1263 |
| RRID | AB_2299937 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q9H4B4 |
| 储存缓冲液 | PBS only , pH 7.3 |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
PLK3(Polo-like kinase 3) is also named as CNK, FNK, PRK and belongs to the protein kinase superfamily. It is involved in the regulation of DNA damage checkpoint as well as in M-phase function. Plk3 physically interacts with p53 and phosphorylates this tumor suppressor protein on serine-20, suggesting that the role of Plk3 in cell cycle progression is mediated, at least in part, through direct regulation of p53(PMID:12548019).