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PF-4878691

PF-4878691 (3M-852A) 是一种有效的选择性 Toll 样受体 7 激动剂，可将其抗病毒活性与其炎症活性解离。

CAS号

532959-63-0

分子式

C17H23N5O2S

主要靶点

TLR

仅限科研使用

Cat No : CM06673

Print datasheet

Synonyms

3M-852A

验证数据展示

  • CAS No.: 532959-63-0

    PF-4878691
    CAS#: 532959-63-0

产品信息

PF-4878691 is an effective and selective Toll-like receptor 7 agonists modelled. It is used to dissociate its antiviral and inflammatory activities.

CAS号 532959-63-0
分子式 C17H23N5O2S
主要靶点 TLR
主要通路 免疫与炎症
分子量 361.46
纯度 99.30%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 3M-852A

溶解度

DMSO:19.23 mg/mL (53.20 mM),Sonification is recommended.

参考文献

1.Fidock MD, et al. The innate immune response, clinical outcomes, and ex vivo HCV antiviral efficacy of a TLR7 agonist (PF-4878691). Clin Pharmacol Ther. 2011 Jun;89(6):821-9.
2.Horscroft NJ, et al. Antiviral applications of Toll-like receptor agonists. J Antimicrob Chemother. 2012 Apr;67(4):789-801.

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