P-1075

CAS号

60559-98-0

分子式

C12H17N5

主要靶点

Potassium Channel

仅限科研使用

Cat No : CM10640

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Synonyms

adult rabbit cardiomyocytes|COS-7|SUR2-KIR6|Potassium Channel|PotassiumChannel|P1075|P-1075|P 1075|inhibit|Inhibitor|KcsA



产品信息

CAS号 60559-98-0
分子式 C12H17N5
主要靶点 Potassium Channel
主要通路 离子通道
分子量 231.3
纯度 99.35%, 此纯度可做参考,具体纯度与批次有关系,可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 adult rabbit cardiomyocytes|COS-7|SUR2-KIR6|Potassium Channel|PotassiumChannel|P1075|P-1075|P 1075|inhibit|Inhibitor|KcsA

靶点活性

SUR2-KIR6:45 nM(EC50)

溶解度

DMSO:250 mg/mL (1080.85 mM)

参考文献

1.Schwanstecher M, et al. Potassium channel openers require ATP to bind to and act through sulfonylurea receptors. EMBO J. 1998 Oct 1;17(19):5529-35.
2.Oldenburg O, et al. P1075 opens mitochondrial K(ATP) channels and generates reactive oxygen species resulting in cardioprotection of rabbit hearts. J Mol Cell Cardiol. 2003 Sep;35(9):1035-42.

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