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Ozenoxacin

CAS号

245765-41-7

分子式

C21H21N3O3

主要靶点

Antibacterial

仅限科研使用

Cat No : CM02863

Print datasheet

Synonyms

Bacterial|Ozenoxacin|Inhibitor|inhibit|奥泽沙星|T3912|T-3912|T 3912

验证数据展示

  • CAS No.: 245765-41-7

    Ozenoxacin
    CAS#: 245765-41-7

产品信息

CAS号 245765-41-7
分子式 C21H21N3O3
主要靶点 Antibacterial
主要通路 微生物学
分子量 363.41
纯度 99.56%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 Bacterial|Ozenoxacin|Inhibitor|inhibit|奥泽沙星|T3912|T-3912|T 3912

体外活性

Ozenoxacin对临床分离的革兰氏阳性微生物展现了强大的抗菌活性（MICs：0.008至4 mg/L）。它对MRSA、MSSA、MSSE和MRSE菌株表现出良好的活性，这些菌株在gyrA和grlA（parC）基因中有2、3或4种突变[1]。Ozenoxacin能抑制MSSA菌株和S. agalactiae菌株，其抗药性率分别>1010和5.3×1010。Ozenoxacin对突变株的最大MIC值为8 mg/L [2]。

溶解度

DMSO:0.91 mg/mL (2.5 mM)

参考文献

1.López Y, et al. In vitro activity of Ozenoxacin against quinolone-susceptible and quinolone-resistant gram-positive bacteria. Antimicrob Agents Chemother. 2013 Dec;57(12):6389-92.
2.López Y, et al. In vitro selection of mutants resistant to ozenoxacin compared with levofloxacin and ciprofloxacin in Gram-positive cocci. J Antimicrob Chemother. 2015 Jan;70(1):57-61

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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C1   V1   C2   V2