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Octyl gallate

Octyl gallate (Octyl 3,4,5-trihydroxybenzoate) 具有抗菌、抗氧化作用，有选择性和敏感性的荧光特性，广泛用作食品添加剂。它对 HSV-1，水泡性口炎病毒和脊髓灰质炎病毒有显著的抗病毒作用。

CAS号

1034-01-1

分子式

C15H22O5

主要靶点

Antifungal|HSV|Antioxidant|Influenza Virus|Antibacterial|Reactive Oxygen Species

仅限科研使用

Cat No : CM00412

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Synonyms

n-Octylgallate|Gallic acid octyl ester|Octyl 3,4,5-trihydroxybenzoate|Progallin O|Stabilizer GA-8|没食子酸辛酯

验证数据展示

  • CAS No.: 1034-01-1

    Octyl gallate
    CAS#: 1034-01-1

产品信息

1. Octyl Gallate is an antioxidant approved by the US Food and Drug Administration (FDA) as a food additive. 2. Octyl Gallate has antimetastatic activity. 3. Octyl Gallate shows antimicrobial activity against H. pylori, with a minimum inhibitory concentration (MIC) value of 125 ug/mL. 4. Combination therapy with octyl gallate and ferulic acid improves cognition and neurodegeneration in a transgenic mouse model of Alzheimer's disease.5. Octyl Gallate is a potential anticancer agent, it exhibited decreased MCF-7 & MDA-MB-231 survival and induced apoptosis, with IC50 value of 40 uM. 6. Octyl gallate has antiviral activity, it shows an inhibitory effect on the growth of herpes simplex virus type 1 (HSV-1) in HEp-2 or Vero cells. 7. Octyl gallate shows antifungal activity against Saccharomyces cerevisiae ATCC7754 and Zygosaccharomyces bailii ATCC 60483.

CAS号 1034-01-1
分子式 C15H22O5
主要靶点 Antifungal|HSV|Antioxidant|Influenza Virus|Antibacterial|Reactive Oxygen Species
主要通路 代谢|NF-κB信号通路|免疫与炎症|微生物学|氧化还原
分子量 282.33
纯度 99.50%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 n-Octylgallate|Gallic acid octyl ester|Octyl 3,4,5-trihydroxybenzoate|Progallin O|Stabilizer GA-8|没食子酸辛酯

溶解度

Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.:Soluble,DMSO:51 mg/mL(180.6 mM)

参考文献

1.Sales, SM , Roy, A , Antony, L , et al. Octyl gallate and gallic acid isolated from, Terminalia bellarica, regulates normal cell cycle in human breast cancer cell lines[J]. Biomedicine & Pharmacotherapy, 2018, 103:1577-1584.

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