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O4I2

O4I2 是一种 Oct3/4诱导剂，可增强多能干细胞相关基因 Lin28、Sox2和 Nanog 的表达，并抑制 Rex1。

CAS号

165682-93-9

分子式

C12H11ClN2O2S

主要靶点

OCT

仅限科研使用

Cat No : CM05345

Print datasheet

Synonyms

O-4I2|O4I2

验证数据展示

  • CAS No.: 165682-93-9

    O4I2
    CAS#: 165682-93-9

产品信息

O4I2 is an effective Oct3/4 inducer in various human cell lines including human fibroblasts.

CAS号 165682-93-9
分子式 C12H11ClN2O2S
主要靶点 OCT
主要通路 离子通道
分子量 282.75
纯度 99.25%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 O-4I2|O4I2

体外活性

O4I2 activates Oct3/4 expression in HEK293 and embryonal NCCIT cells, and also in Oct-deficient HeLa and terminally differentiated human fibroblasts, and also induces other pluripotency-associated genes such as Lin28 and Nanog. [1]

溶解度

DMSO:28.3 mg/mL (100 mM),Ethanol:14.1 mg/mL (50 mM)

参考文献

1.Cheng X, et al. J Med Chem. 2015 Aug 13;58(15):5742-5750.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
=
×
×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2