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NLRC3 Polyclonal antibody

NLRC3 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

Human

Applications

WB, ELISA

Conjugate

Unconjugated

Cat No : 30455-1-AP

Print datasheet

Synonyms

CARD15 like protein, Caterpiller protein 16.2, CLR16.2, FLJ00348, NLRC3, NOD3, Protein NLRC3

验证数据展示

  • WB analysis using 30455-1-AP

    WB analysis using 30455-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 30455-1-AP (NLRC3 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inDaudi cells, Jurkat cells, Raji cells, Ramos cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:4000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

30455-1-AP targets NLRC3 in WB, ELISA applications and shows reactivity with Human samples.

Tested Applications WB, ELISA
Tested Reactivity Human
Immunogen NLRC3 fusion protein Ag32323 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name NLR family, CARD domain containing 3
Synonyms CARD15 like protein, Caterpiller protein 16.2, CLR16.2, FLJ00348, NLRC3, NOD3, Protein NLRC3
Calculated Molecular Weight 115 kDa
Observed Molecular Weight100-110 kDa
GenBank Accession NumberNM_178844
Gene Symbol NLRC3
Gene ID (NCBI) 197358
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ7RTR2
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

NLRC3 is a member of the pattern recognition receptors nucleotide-binding oligomerization domain (NOD)-like receptors (NLRs) family, and plays a pivotal regulatory role in modulating the activation of immune cells. In macrophages, NLRC3 inhibits the activation of the NF-κB signaling pathway, the STING/TBK1 signaling pathway, and the formation of the inflammasome. In the context of T cells immune response, NLRC3 prevents the activation of T cells by regulating the function of dendritic cells and directly influencing the function of T cells.

实验方案

Product Specific Protocols
WB protocol for NLRC3 antibody 30455-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols