NCB-0846

CAS号

1792999-26-8

分子式

C21H21N5O2

主要靶点

Wnt/beta-catenin|MAPK

仅限科研使用

Cat No : CM06691

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Synonyms

Inhibitor|MAP4K|MAPK Kinase Kinase Kinase|NCB 0846|NCB0846|NCB-0846|Wnt|Wnt/b-catenin|Wnt/betacatenin|Wnt/β-catenin|βcatenin|TNIK|inhibit|beta-catenin|betacatenin|bcatenin



产品信息

CAS号 1792999-26-8
分子式 C21H21N5O2
主要靶点 Wnt/beta-catenin|MAPK
主要通路 MAPK 信号通路|干细胞|细胞骨架
分子量 375.42
纯度 99.46%, 此纯度可做参考,具体纯度与批次有关系,可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 Inhibitor|MAP4K|MAPK Kinase Kinase Kinase|NCB 0846|NCB0846|NCB-0846|Wnt|Wnt/b-catenin|Wnt/betacatenin|Wnt/β-catenin|βcatenin|TNIK|inhibit|beta-catenin|betacatenin|bcatenin

靶点活性

TNIK:21?nM

溶解度

DMSO:50 mg/mL (133.18 mM)

参考文献

1.Masuda M, et al. TNIK inhibition abrogates colorectal cancer stemness. Nat Commun. 2016 Aug 26;7:12586.

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