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Mycaminosyltylonolide

Mycaminosyltylonolide 是一种大环内酯类抗生素，它是 tyololide 在位置5上具有β - d -mycaminosyl 残基。Mycaminosyltylonolide 是一种有效的抗生素，具有抗菌活性和抑制荧光素酶的合成。

CAS号

61257-02-1

分子式

C31H51NO10

主要靶点

Antibacterial

仅限科研使用

Cat No : CM11433

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Synonyms

验证数据展示

  • CAS No.: 61257-02-1

    Mycaminosyltylonolide
    CAS#: 61257-02-1

产品信息

Mycaminosyltylonolide is a macrolide antibiotic that is tylonolide having a beta-D-mycaminosyl residue attached at position 5. Mycaminosyltylonolide is a potent antibiotic with antibacterial activity and inhibits luciferase synthesis.

CAS号 61257-02-1
分子式 C31H51NO10
主要靶点 Antibacterial
主要通路 微生物学
分子量 597.74
纯度 97.80%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件
别名

体外活性

Mycaminosyltylonolide(3µM) inhibits firefly luciferase mRNA translation in E. coli S30 [1]. Mycaminosyltylonolide(0-128 µg/mL) shows antibacterial activity with MIC values of 1, 1, 2, 2, 1, 64 µg/mL for S. aureus FDA209Pa, S. aureus Smitha, S. aureus KUB857c, S. epidermidis KUB795g, E. faecalis ATCC29212h, K. pneumoniae NCTC9632h, respectively [2].

溶解度

DMSO:30 mg/mL (50.19 mM)

参考文献

1.Shishkina A, et al. Conjugates of amino acids and peptides with 5-o-mycaminosyltylonolide and their interaction with the ribosomal exit tunnel. Bioconjug Chem. 2013 Nov 20;24(11):1861-9.
2.Sugawara A, et al. 5-O-Mycaminosyltylonolide antibacterial derivatives: design, synthesis and bioactivity. J Antibiot (Tokyo). 2017 Jul;70(8):878-887.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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