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MultiProTM 5CFLX Anti-Human MFN2 (5F3B3)

MFN2 Monoclonal Antibody for Single Cell (Intra)

Host / Isotype

Mouse / IgG2a

Reactivity

Human

Applications

Single Cell (Intra)

Conjugate

5CFLX

Barcode Sequence

CGCCACCAATGACCT

CloneNo.

5F3B3

Cat No : G67487-1-5C

Print datasheet

Synonyms

CMT2A, CMT2A2, CPRP1, HSG, KIAA0214, MARF, MFN2, mitofusin 2, Transmembrane GTPase MFN2

验证数据展示

  • Single Cell Sequencing experiment G67487-1-5C on Resting PBMC

    Single Cell Sequencing experiment G67487-1-5C on Resting PBMC

    G67487-1-5C was used to stain Resting PBMC and analyzed with 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing kit with Fix-Stain protocol.

  • Single Cell Sequencing experiment G67487-1-5C on PBMC treated with 4hr LPS + TI

    Single Cell Sequencing experiment G67487-1-5C on PBMC treated with 4hr LPS + TI

    G67487-1-5C was used to stain PBMC under 4hr LPS + TI treatment and analyzed with 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing kit with Fix-Stain protocol.

经过测试的应用

Positive Single Cell (Intra) detected in10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product.

推荐稀释比

ApplicationDilution
SINGLE CELL (INTRA)<0.5ug/test
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

产品信息

G67487-1-5C targets MFN2 in applications and shows reactivity with Human samples.

Tested Applications Single Cell (Intra)
Tested Reactivity Human
Immunogen MFN2 fusion protein Ag29873 种属同源性预测
Host / Isotype Mouse / IgG2a
Class Oligo Conjugate
Type Monoclonal
Full Name MultiProTM 5CFLX Anti-Human MFN2 (5F3B3)
Synonyms CMT2A, CMT2A2, CPRP1, HSG, KIAA0214, MARF, MFN2, mitofusin 2, Transmembrane GTPase MFN2
Calculated Molecular Weight 757 aa, 86 kDa
GenBank Accession NumberBC017061
Gene Symbol MFN2
Gene ID (NCBI) 9927
ENSEMBL Gene IDENSG00000116688
Conjugate 5CFLX
Full Oligo SequenceCGGAGATGTGTATAAGAGACAGCGCCACCAATGACCTCCCATATAAGAAA
Barcode SequenceCGCCACCAATGACCT
Form Liquid
UNIPROT IDO95140
Storage Buffer PBS with 1mM EDTA and 0.09% sodium azide
Storage Conditions2-8°C

背景介绍

MFN2, also named as CPRP1 and KIAA0214, belongs to the mitofusin family. It is an Essential transmembrane GTPase, which mediates mitochondrial fusion. MFN2 acts independently of the cytoskeleton. It therefore plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. Overexpression of MFN2 induces the formation of mitochondrial networks. It plays an important role in the regulation of vascular smooth muscle cell proliferation. Defects in MFN2 are the cause of Charcot-Marie-Tooth disease type 2A2 (CMT2A2). Defects in MFN2 are the cause of Charcot-Marie-Tooth disease type 6 (CMT6). Ubiquitinated forms of Mfn2 (mono- and polyubiquitinated) are present during mitophagy.

Protocols

Our current MultiPro staining protocol for the cocktailDownload protocol
10x Genomics CG000149_Demonstrated Protocol CellSurface Protein Labeling_Rev D.pdfDownload protocol