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Recombinant Mouse Transferrin R/CD71 protein (rFc Tag)

种属

Mouse

纯度

>90 %, SDS-PAGE

标签

rFc Tag

生物活性

未测试

Cat no : Eg3385

Print datasheet

Synonyms

CD71, Tfrc, TFR, TFR1, TR

验证数据展示

  • Purity of Recombinant Mouse Transferrin R was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) conditions and stained using Coomassie blue.

    Purity of Recombinant Mouse Transferrin R was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) conditions and stained using Coomassie blue.

产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 
Not tested
来源 HEK293-derived Mouse Transferrin R protein Cys89-Phe763 (Accession# Q62351) with a rabbit IgG Fc tag at the N-terminus.
基因ID 22042
蛋白编号 Q62351
预测分子量 103.1 kDa
SDS-PAGE 95-125 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

The transferrin receptor is a membrane glycoprotein whose only clearly defined function is to mediate cellular uptake of iron from a plasma glycoprotein, transferrin. Iron uptake from transferrin involves the binding of transferrin to the transferrin receptor, internalization of transferrin within an endocytic vesicle by receptor-mediated endocytosis and the release of iron from the protein by a decrease in endosomal pH. With the exception of highly differentiated cells, transferrin receptors are probably expressed on all cells but their levels vary greatly. Transferrin receptors are highly expressed on immature erythroid cells, placental tissue, and rapidly dividing cells, both normal and malignant.

参考文献:

1. Chiappelli F. et al. (2024) Bioinformation. 20(3):208-211.
2. D'Aprile S. et al. (2023) J Transl Med. 21(1):780.
3. Liu X. et al. (2023) Asian J Pharm SCI. 18(4):100826.
4. Grzywa T. et al. (2022) BLOOD. 140(Supple 1):8166-8167.