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Recombinant Mouse TNFRSF13B/CD267 protein (rFc Tag)

种属

Mouse

纯度

>90 %, SDS-PAGE

标签

rFc Tag

生物活性

未测试

Cat no : Eg1814

Print datasheet

Synonyms

CD267, Taci, Tnfrsf13b, Transmembrane activator and CAML interactor, Tumor necrosis factor receptor superfamily member 13B

验证数据展示

  • Purity of Recombinant Mouse TNFRSF13B was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Mouse TNFRSF13B was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 
Not tested
来源 HEK293-derived Mouse TNFRSF13B protein Phe5-Cys128 (Accession# Q9ET35) with a rabbit IgG Fc tag at the C-terminus.
基因ID 57916
蛋白编号 Q9ET35
预测分子量 40.3 kDa
SDS-PAGE 40-48 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

Tumor necrosis factor receptor superfamily member 13B (TNFRSF13B), also known as CD267 or TACI, is a transmembrane protein of the TNF receptor superfamily found predominantly on B cells. TACI is also expressed on activated T cells, myeloma cells, and expressed by monocytes intracellularly at a low level. TNFRSF13B is a receptor for TNFSF13/APRIL/CD256 and TNFSF13B/BAFF/CD257 and mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-κB and AP-1. It is involved in the stimulation of B- and T-cell function and the regulation of humoral immunity.

参考文献:

1.von Bülow GU, et al. (2000) Mamm Genome. 11(8):628-32.
2.Wang H, et al. (2001) Nat Immunol. 2(7):632-7.
3.Chang SK, et al. (2006) Blood. 108(8):2687-94.
4.Wu Y, et al. (2000) J Biol Chem. 275(45):35478-85.
5.Yu G, et al. (2000) Nat Immunol. 1(3):252-6.
6.von Bülow GU, Bram RJ. (1997) Science. 278(5335):138-41.