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Morroniside

Morroniside 通过抑制神经元凋亡和 MMP9/2 的表达从而发挥神经保护作用，可作为 db/db 小鼠肝脏炎症反应和脂质代谢的调节剂。它通过抑制高血糖和氧化应激表现出对糖尿病肾损伤和人脐静脉内皮细胞的保护作用。

CAS号

25406-64-8

分子式

C17H26O11

主要靶点

Apoptosis|Pyroptosis|MMP

仅限科研使用

Cat No : CM04874

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Synonyms

莫诺苷|奎宁树

验证数据展示

  • CAS No.: 25406-64-8

    Morroniside
    CAS#: 25406-64-8

产品信息

Morroniside would act as a regulator of hepatic inflammatory reactions and lipid metabolism in db/db mice. It exhibits protective effects against diabetic renal damage and human umbilical vein endothelial cells, by inhibiting hyperglycemia and oxidative stress. Morroniside can notably protect the brain from damage induced by focal cerebral ischemia which might be related to morroniside antioxidant and anti-apoptotic properties in the brain.

CAS号 25406-64-8
分子式 C17H26O11
主要靶点 Apoptosis|Pyroptosis|MMP
主要通路 免疫与炎症|凋亡|蛋白酶体
分子量 406.38
纯度 99.40%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 莫诺苷|奎宁树

溶解度

Ethanol:73 mg/mL(179.6 mM),Pyridine, Methanol:Soluble

参考文献

1.Xiong S, et al. J Pharmacol Sci. 2015 Apr;127(4):414-8.
2.Sun FL, et al. Eur J Pharmacol. 2014 Sep 5;738:214-21.
3.Cheng L, et al. J Cell Mol Med. 2015 Aug;19(8):1877-86.
4.Sun FL, et al. PLoS One. 2014 Jun 30;9(6):e1201194.

The molarity calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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C1   V1   C2   V2