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Mitiglinide calcium hydrate

Mitiglinide calcium hydrate (S-21403 calcium hydrate) 是一种 ATP 敏感的 K+通道 (KATPchannel) 拮抗剂， 属于促胰岛素化合物。它对 Kir6.2/SUR1 复合物 (胰腺-细胞 KATP 通道) 具有高度特异性，在 2 型糖尿病中有研究价值。

CAS号

207844-01-7

分子式

C38H52CaN2O8

主要靶点

Potassium Channel

仅限科研使用

Cat No : CM06091

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Synonyms

Mitiglinide calcium|KAD-1229 calcium hydrate|米格列奈钙|S-21403 calcium hydrate

验证数据展示

  • CAS No.: 207844-01-7

    Mitiglinide calcium hydrate
    CAS#: 207844-01-7

产品信息

Mitiglinide calcium hydrate (S-21403 calcium hydrate) is a drug for the treatment of type 2 diabetes. Mitiglinide is thought to stimulate insulin secretion by closing the ATP-sensitive K(+) K(ATP) channels in pancreatic beta-cells. Mitiglinide belongs to the meglitinide class of blood glucose-lowering drugs and is currently co-marketed in Japan by Kissei and Takeda.

CAS号 207844-01-7
分子式 C38H52CaN2O8
主要靶点 Potassium Channel
主要通路 离子通道
分子量 704.91
纯度 100.00%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 Mitiglinide calcium|KAD-1229 calcium hydrate|米格列奈钙|S-21403 calcium hydrate

溶解度

DMSO:25 mg/mL (35.47 mM)

参考文献

1.Malaisse WJ. Expert Opin PharmacOthers. 2008 Oct;9(15):2691-8.

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The dilution calculator equation

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