Methyl 5-hydroxypyridine-2-carboxylate

Methyl 5-hydroxypyridine-2-carboxylate 是存在于 Mahonia fortune 茎中的一种酚酸,在体外表现出 NO 抑制活性。

CAS号

30766-12-2

分子式

C7H7NO3

主要靶点

Others

仅限科研使用

Cat No : CM11659

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Synonyms



产品信息

Methyl 5-hydroxypyridine-2-carboxylate is a phenolic acid found in the stems of Mahonia fortune. Methyl 5-hydroxypyridine-2-carboxylate exhibits NO inhibitory effects in vitro.

CAS号 30766-12-2
分子式 C7H7NO3
主要靶点 Others
主要通路 其他
分子量 153.14
纯度 , 此纯度可做参考,具体纯度与批次有关系,可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名

体外活性

Methyl 5-hydroxypyridine-2-carboxylate (compound 2) inhibits NO in LPS-stimulated RAW264.7 and BV2 cells, with IC 50 s of 115.67 and 118.80 μM, respectively [1]. Methyl 5-hydroxypyridine-2-carboxylate (6.25-200μM) does not have any cytotoxic effect [1].

溶解度

DMSO:50 mg/mL (326.50 mM),Sonification is recommended.

参考文献

1.Liu L, et, al. Simultaneous characterisation of multiple Mahonia fortunei bioactive compounds in rat plasma by UPLC-MS/MS for application in pharmacokinetic studies and anti-inflammatory activity in vitro. J Pharm Biomed Anal. 2020 Feb 5;179:113013.

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