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Mepyramine maleate

Mepyramine maleate (Pyrilamine maleate) 是一种组胺 H1 拮抗剂，对 H1、H2 和 H3 受体的 Kd 值分别为 0.8、5200 和大于 3000 nM，对 H1 受体的 pKd 值为 9.4。它是感冒药的常见成分，具有温和的催眠特性和局部麻醉作用，可用于胃肠外和局部过敏。

CAS号

59-33-6

分子式

C21H27N3O5

主要靶点

Histamine Receptor

仅限科研使用

Cat No : CM04499

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Synonyms

Pyrilamine maleate|马来酸吡纳明|吡拉明马来酸盐

验证数据展示

  • CAS No.: 59-33-6

    Mepyramine maleate
    CAS#: 59-33-6

产品信息

Pyrilamine maleate is a histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both parenterally and locally. It is a common ingredient of cold remedies.

CAS号 59-33-6
分子式 C21H27N3O5
主要靶点 Histamine Receptor
主要通路 神经科学|G蛋白偶联受体|免疫与炎症
分子量 401.47
纯度 99.71%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 Pyrilamine maleate|马来酸吡纳明|吡拉明马来酸盐

溶解度

DMSO:40.2 mg/mL(100 mM)

参考文献

1.Moriyama K, et al. Inflamm Res. 2009 Dec;58(12):873-80.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
=
×
×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2