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Menthone

CAS号

10458-14-7

分子式

C10H18O

主要靶点

Parasite|IL Receptor|NF-κB|TNF

仅限科研使用

Cat No : CM00349

Print datasheet

Synonyms

TNF-α|volatile|薄荷酮|Parasite|NF-kB|NFkB|NF-κB|NFκB|Inhibitor|Menthone|anti-Inflammatory|antioxidant|inhibit|IL Receptor|IL receptor|ILReceptor

验证数据展示

  • CAS No.: 10458-14-7

    Menthone
    CAS#: 10458-14-7

产品信息

CAS号 10458-14-7
分子式 C10H18O
主要靶点 Parasite|IL Receptor|NF-κB|TNF
主要通路 NF-κB 信号通路|凋亡|免疫与炎症|微生物学
分子量 154.25
纯度 ≥95%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 TNF-α|volatile|薄荷酮|Parasite|NF-kB|NFkB|NF-κB|NFκB|Inhibitor|Menthone|anti-Inflammatory|antioxidant|inhibit|IL Receptor|IL receptor|ILReceptor

体内活性

Menthone和Vit C在较高剂量下对于男性大鼠生殖系统中ACV所引起的不利影响具有良好的补偿作用，能显著降低精子细胞的DNA损伤。

溶解度

DMSO:30 mg/mL (194.49 mM)

动物实验

Adult male albino Wistar rats with average weight of 250±10 gr, were divided into six groups (n=18/each), as: ACV (15 mg/kg/day), ACV+Vit C (20 mg/kg/day), ACV+ menthone (100 μl/d), ACV+ menthone (250 μl/d), ACV+ menthone (400 μl/day) and control group without any treatment. At the end of experiment, the animals were sacrificed and sperm samples were collected and isolated in phosphate-buffered saline and examined by TUNEL staining process. The percentage of TUNEL positive spermatozoa was evaluated by fluorescence microscopy. Each experiment was performed in three repeats

参考文献

1.Toghiani S, Hayati Roudbari N, Dashti GR, Rouzbehani S.The effects of vitamin C and menthone on acyclovir induced DNA damage in rat spermatozoa: An experimental study.[J].Int J Reprod Biomed (Yazd). 2018 Nov;16(11):703-710.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
=
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
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C1   V1   C2   V2