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Maytansine

CAS号

35846-53-8

分子式

C34H46ClN3O10

主要靶点

Antibiotic|Microtubule Associated

仅限科研使用

Cat No : CM05133

Print datasheet

Synonyms

mitotic|MicrotubuleAssociated|microtubule-targeted|microtubule|Microtubule Associated|Microtubule/Tubulin|Maytansine|Maitansina|Maitansine|inhibit|Inhibitor|potent|NSC153858|NSC-153858|NSC 153858|subnanomolar|tumor|美坦新|arrest|Antibiotic

验证数据展示

  • CAS No.: 35846-53-8

    Maytansine
    CAS#: 35846-53-8

产品信息

CAS号 35846-53-8
分子式 C34H46ClN3O10
主要靶点 Antibiotic|Microtubule Associated
主要通路 微生物学|细胞骨架
分子量 692.2
纯度 99.62%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 mitotic|MicrotubuleAssociated|microtubule-targeted|microtubule|Microtubule Associated|Microtubule/Tubulin|Maytansine|Maitansina|Maitansine|inhibit|Inhibitor|potent|NSC153858|NSC-153858|NSC 153858|subnanomolar|tumor|美坦新|arrest|Antibiotic

溶解度

H2O:Insoluble;DMSO:60 mg/ml (86.68 mM)

参考文献

1.Kusari S, Lamsh?ft M, Kusari P, Gottfried S, Zühlke S, Louven K, Hentschel U, Kayser O, Spiteller M. Endophytes are hidden producers of maytansine in Putterlickia roots. J Nat Prod. 2014 Dec 26;77(12):2577-84.
2.Tang X, Dai H, Zhu Y, Tian Y, Zhang R, Mei R, Li D. Maytansine-loaded star-shaped folate-core PLA-TPGS nanoparticles enhancing anticancer activity. Am J Transl Res. 2014 Oct 11;6(5):528-37. eCollection 2014.
3.Wings S, Müller H, Berg G, Lamsh?ft M, Leistner E. A study of the bacterial community in the root system of the maytansine containing plant Putterlickia verrucosa. Phytochemistry. 2013 Jul;91:158-64.
4.Lopus M, Oroudjev E, Wilson L, Wilhelm S, Widdison W, Chari R, Jordan MA. Maytansine and cellular metabolites of antibody-maytansinoid conjugates strongly suppress microtubule dynamics by binding to microtubules. Mol Cancer Ther. 2010 Oct;9(10):2689-99.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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