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Host
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Species Reactivity
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Conjugate
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验证数据展示

  • WB analysis using 13278-1-AP (same clone as 13278-1-PBS)

    WB analysis using 13278-1-AP (same clone as 13278-1-PBS)

    Untreated and IFN beta treated THP-1 cell lysates were subjected to SDS PAGE followed by western blot with 13278-1-AP (MX2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13278-1-PBS in a different storage buffer formulation.

  • IHC staining of human stomach using 13278-1-AP (same clone as 13278-1-PBS)

    IHC staining of human stomach using 13278-1-AP (same clone as 13278-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human stomach tissue slide using 13278-1-AP (MX2 antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13278-1-PBS in a different storage buffer formulation.

MX2 Polyclonal antibody, PBS Only

MX2 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 13278-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, Indirect ELISA

别名

p78-related protein, p78 related protein, Myxovirus resistance protein 2, MXB, Interferon-regulated resistance GTP-binding protein MxB

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

13278-1-PBS targets MX2 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原 MX2 fusion protein Ag4020 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 myxovirus (influenza virus) resistance 2 (mouse)
别名 p78-related protein, p78 related protein, Myxovirus resistance protein 2, MXB, Interferon-regulated resistance GTP-binding protein MxB
计算分子量 715 aa, 82 kDa
观测分子量 70-82 kDa
GenBank蛋白编号BC035293
基因名称 MX2
Gene ID (NCBI) 4600
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP20592
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Myxovirus resistance 2 (MX2, also known as MxB) is a member of both the dynamin family and the family of large GTPases. MX2 is an interferon-stimulated gene that inhibits the nuclear import of HIV-1 and interacts with the viral capsid and cellular nuclear transport machinery. MX2 mediates the effects of IFN signaling in a cell type and context-dependent manner that can influence cells sensitivity to MAPK pathway targeted therapies. MX2 is also associated with the tumorigenesis process in melanoma(PMID: 33734579).